Analyst Upside

AU · rank #3 · 2026-05-15

PRLD

NASDAQ · $356M

verdict · CAUTION

Why this pick · factor scores

The exact numbers the algorithm saw.

Composite score
Z-score blend of all factors below.
3.036
EPS revisions (30d)
Net up-revisions in consensus EPS over the past month.
-91.00%
Net revisions (30d)
Number of analysts revising upward minus downward.
1
Insider signal (90d)
$12,499,999 across 1 unique buyers.
8.366
Analyst upside
Consensus target $6.88
+53.8%
Momentum acceleration
3-month minus 12-month momentum.
+6.18%
Analyst rating
1 = Strong Buy, 5 = Strong Sell.
3.75
Gross margin TTM+100.0%
52w high$5.54
Market cap$356M

AI research card

Independent qualitative review before order placement.

Summary

Prelude Therapeutics Inc. is a clinical-stage precision oncology company focused on discovering and developing novel small molecule cancer medicines for patients with high unmet medical needs.

Rationale

The significant analyst upside of 53.80% and recent substantial insider buying totaling nearly $12.5 million by a director suggest strong conviction in future performance, despite recent negative EPS revisions.

Material risks

  • 1Prelude Therapeutics is currently unprofitable and is not projected to achieve profitability within the next three years, indicating ongoing cash burn and potential need for further capital raises.
  • 2The company's shareholders have experienced substantial dilution over the past year, with total shares outstanding increasing by 32.4%, which could continue with future equity offerings.

Verdict reasoning

While insider buying and analyst upside are strong signals, the company's unprofitability and history of shareholder dilution present considerable risks.