Analyst Upside

AU · rank #4 · 2026-05-18

PRLD

NASDAQ · $356M

verdict · CAUTION

Why this pick · factor scores

The exact numbers the algorithm saw.

Composite score
Z-score blend of all factors below.
2.755
EPS revisions (30d)
Net up-revisions in consensus EPS over the past month.
-83.33%
Net revisions (30d)
Number of analysts revising upward minus downward.
1
Insider signal (90d)
$12,499,999 across 1 unique buyers.
7.999
Analyst upside
Consensus target $6.88
+53.5%
Momentum acceleration
3-month minus 12-month momentum.
+10.51%
Analyst rating
1 = Strong Buy, 5 = Strong Sell.
3.75
Gross margin TTM+100.0%
52w high$5.54
Market cap$356M

AI research card

Independent qualitative review before order placement.

Summary

Prelude Therapeutics Inc. is a clinical-stage precision oncology company focused on discovering and developing novel small molecule therapies for cancer patients with high unmet needs.

Rationale

The significant analyst upside potential of 53.46% and strong insider buying activity suggest a belief in future stock appreciation despite recent negative EPS revisions.

Material risks

  • 1As a clinical-stage biotechnology company, PRLD's success is highly dependent on the outcome of ongoing and future clinical trials for its drug candidates.
  • 2The company has a limited cash runway, with existing funds anticipated to last into the second quarter of 2028, necessitating further financing or successful drug development.

Verdict reasoning

While analyst sentiment and insider buying are positive, the inherent risks of clinical-stage oncology development and limited cash runway warrant caution.